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Chelora Agrochemicals

Aromatic & fine-chemical intermediates

High-purity building blocks for crop protection, dye and fine-chemical synthesis, each shipped with a full COA and SDS.

45compounds across four
reference families
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AAnilines & amine intermediates
Methyl Ethyl Aniline 3,4-Dichloro Aniline 2,5-Dichloro Aniline Ortho Nitro Aniline Para Fluoro Aniline Para Chloro Aniline Ortho Phenylene Diamine Para Toluidine 4-Fluoro-N-Isopropylaniline 2,4-Dichloroaniline 2,6-Dichloroaniline Ortho Ethyl Aniline 2,6-Diethylaniline 2,3,4-Trifluoroaniline Ortho Fluoro Aniline 2,6-Difluoroaniline Meta Chloro Aniline 3-Chloro-2-Methylaniline 5-Chloro-2-Methylaniline 2,6-Diisopropylaniline 2,6-Diethyl-N-Propoxyethyl Aniline
BNitro & halo benzenes
Para Nitro Chloro Benzene Nitro Benzene Ortho Nitro Chloro Benzene 3,4-Dichloro Nitro Benzene 2,4-Difluoro Nitro Benzene 1,2,4-Trichloro Benzene 2,3-Dichloro Nitro Benzene 2,6-Dichloro Fluoro Benzene Meta Dichloro Benzene Para Fluoro Nitro Benzene 2,4-Dichloro Fluoro Benzene 1,2,3-Trichloro Benzene 2,3,4-Trichloro Nitro Benzene 2,3,4-Trifluoro Nitro Benzene 2,4-Dinitro Fluoro Benzene
CPhenols & specialty aromatics
2,5-Dichloro Phenol 3,4,5-Trifluoro Bromo Benzene 2,6-Difluoro Benzonitrile 2-Bromo-4-Fluoro Acetanilide Diisopropyl Isothiocyanato Phenoxybenzene 2-Hydrazino-4-Methylbenzothiazole
CAcids & inorganic salts
Sulfuric Acid Di Methyl Sulfate Potassium Fluoride
DDirectory
All agrochemical products Request a sample Talk to the technical team
DAbout this range

Aromatic intermediates for crop protection, dye and fine-chemical synthesis — 45 products across four reference families, each shipped with a full COA and SDS.

Fluoroquinolone intermediate

2,4-Dichloro Fluoro Benzene (2,4-DCFB) Supplier & Distributor in India & Worldwide

Chelora Agrochem is a trusted 2,4-Dichloro Fluoro Benzene (2,4-DCFB) supplier and distributor in India, connecting buyers with high-purity material sourced from leading, quality-approved manufacturers. Our 2,4-dichloro-1-fluorobenzene meets 99.5% min purity with controlled isomer content, full documentation and reliable bulk supply across India and to buyers worldwide.

As a specialised distributor of chemical products, we do not manufacture in-house — instead we source only from reliable, audited manufacturers, giving you dependable material, competitive pricing and a single point of contact for all your 2,4-DCFB requirements, backed by COA, MSDS and TDS on every order.

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CAS number
1435-48-9
Formula
C6H3Cl2F
Molecular weight
164.99 g/mol
Purity
99.5% min
HS code2903 99 TransportClassification stated on SDS Packing250 kg drums, IBCs, ISO tanks MOQDrums to container loads DocumentationCOA · MSDS · TDS SupplyPan-India & worldwide export

Quick product specifications

2,4-Dichloro Fluoro Benzene at a glance

Identifiers, physical data and trade codes for 2,4-DCFB. Batch-specific figures are confirmed on the Certificate of Analysis supplied with each consignment, in India and on export shipments alike.

Chemical name
2,4-Dichloro Fluoro Benzene
CAS number
1435-48-9
Molecular formula
C6H3Cl2F
Molecular weight
164.99 g/mol
IUPAC name
2,4-Dichloro-1-fluorobenzene
HS code
2903 99National subheading as per destination
Transport
As stated on the SDSDepends on flash point and environmental classification
Appearance
Clear colourless liquid
Boiling point
About 172–174 °C
Density
About 1.41 g/mLAt 25 °C
Flash point
About 65 °CClosed cup, combustible liquid
Solubility
Practically insoluble in waterMiscible with common organic solvents
Purity
99.5% min
Synonyms
2,4-DCFB1,3-Dichloro-4-fluorobenzene · 2,4-Dichlorofluorobenzene
Product form
Liquid — drums, IBCs, ISO tanks
Isomer control
2,6-DCFB and other isomers by GC
Main downstream
2,4-Dichloro-5-fluorobenzoyl chloride
Documentation
COA, MSDS & TDSSupplied with every order

Product overview

What is 2,4-Dichloro Fluoro Benzene?

2,4-Dichloro Fluoro Benzene (2,4-DCFB) is a halogenated benzene used mainly as the starting material for 2,4-dichloro-5-fluoroacetophenone and 2,4-dichloro-5-fluorobenzoyl chloride — the key intermediates for the fluoroquinolone antibiotic ciprofloxacin.

With the formula C6H3Cl2F (CAS 1435-48-9), 2,4-DCFB is a clear colourless liquid that boils at about 173 °C and is practically insoluble in water. It is produced by introducing fluorine into a dichloro-aromatic precursor and purified by distillation.

Friedel–Crafts acylation of 2,4-DCFB goes to the position between the fluorine and a chlorine, setting the substitution pattern of the quinolone ring — so isomer purity at this stage decides the quality of the final antibiotic intermediate.

How it is made

2,4-DCFB is made by introducing fluorine into the corresponding dichloro-aromatic precursor — for example by diazotisation and fluorination of 2,4-dichloroaniline — and is separated from related isomers by fractional distillation.

What that means for your process

  • Directs acylation to the 5-position for quinolone synthesis
  • 2,6-isomer and other isomers controlled, checked by GC
  • Low moisture for Friedel–Crafts acylation
  • Distilled, colourless liquid

Applications

What is 2,4-Dichloro Fluoro Benzene used for?

2,4-DCFB is used almost entirely as a chemical intermediate. Its main applications, industry by industry, include:

Fluoroquinolone antibiotics

The main use. Acylated to 2,4-dichloro-5-fluoroacetophenone and converted to 2,4-dichloro-5-fluorobenzoyl chloride for ciprofloxacin.

  • Precursor of 2,4-dichloro-5-fluoroacetophenone
  • Route to 2,4-dichloro-5-fluorobenzoyl chloride
  • Ciprofloxacin and related quinolones

Agrochemicals

A fluoro-chloro building block for crop-protection actives.

  • Fluoro-chloro phenyl intermediates
  • Fluorinated insecticide and herbicide building blocks

Fine chemicals

Specified by custom-synthesis houses for halogenated aromatic intermediates.

  • Liquid-crystal and material intermediates
  • Custom synthesis and research scale-up

Process route

How is 2,4-DCFB used in ciprofloxacin manufacturing?

2,4-DCFB is acetylated by Friedel–Crafts reaction to 2,4-dichloro-5-fluoroacetophenone. Oxidation and chlorination give 2,4-dichloro-5-fluorobenzoyl chloride, which is built into the quinolone ring of ciprofloxacin.

1

2,4-Dichloro Fluoro Benzene

Charged as the halogenated aromatic. Isomer purity decides the purity of the acylated product.

C6H3Cl2F
2

Friedel–Crafts acylation

Acetylated with acetyl chloride over aluminium chloride.

CH3COCl / AlCl3
3

Acetophenone intermediate

2,4-Dichloro-5-fluoroacetophenone, converted to the benzoyl chloride.

DCFA → acid chloride
4

Antibiotic API

Quinolone ring construction gives ciprofloxacin.

Ciprofloxacin

In depth

2,4-Dichloro Fluoro Benzene applications by industry

Below is a detailed breakdown of where 2,4-DCFB is used and the role it plays in each downstream product.

IndustryTypical downstream productsRole of 2,4-DCFB
Pharmaceuticals2,4-Dichloro-5-fluoroacetophenone, benzoyl chloride, ciprofloxacinStarting material
AgrochemicalsFluoro-chloro phenyl activesBuilding block
Fine chemicalsMaterial and custom intermediatesBuilding block

Safety

Is 2,4-Dichloro Fluoro Benzene hazardous?

Yes, with moderate hazards. 2,4-DCFB irritates the skin, eyes and respiratory tract, is a combustible liquid, and is toxic to aquatic life with long-lasting effects. With correct PPE, ventilation and storage it is safely handled in industry.

2,4-DCFB should be stored in sealed containers in a cool, dry, ventilated place away from heat, ignition sources and strong oxidisers, and handled with gloves, goggles and vapour respiratory protection where needed. Prevent release to drains and waterways. A full MSDS is supplied with every order.

Ask for the full MSDS

Signal word: Warning

Skin, eye and respiratory irritant · combustible liquid · toxic to aquatic life

Safe-handling essentials

  • Gloves, goggles and protective clothing at all times
  • Use local exhaust ventilation; avoid breathing vapour
  • Keep away from heat, sparks and open flames; earth equipment
  • Keep drums sealed, cool and dry
  • Store away from strong oxidisers
  • Never allow release to drains, soil or waterways
  • Transport classification as stated on the SDS

Grades

2,4-Dichloro Fluoro Benzene grades & technical specifications

We supply 2,4-DCFB in a high-purity grade with tight isomer control for fluoroquinolone synthesis.

ParameterSpecification
Assay (purity)99.5% min
AppearanceClear colourless liquid
2,6-Dichlorofluorobenzene0.2% max
Other isomers0.2% max
Moisture0.05% max
ColourAPHA 20 max
Density at 25 °C1.405 – 1.415 g/mL
Product formLiquid — drums, IBCs, ISO tanks

Note: Values are representative. Batch-specific figures are provided on the Certificate of Analysis (COA) supplied with each consignment.

Supply

Packaging, MOQ & supply

From trial quantities for process validation to repeat container loads on contract — packed, documented and dispatched to your plant in India or overseas.

Packaging

250 kg HDPE or MS drums, IBCs and ISO tanks as per quantity.

Minimum order quantity

Flexible — single drums or bags for trials through to full-container loads.

Shelf life

Long shelf life in sealed, unopened containers stored cool, dry and away from heat sources.

Dispatch

Pan-India dispatch and worldwide export with complete dangerous-goods documentation and logistics support.

Why buy from us

Why choose Chelora as your 2,4-DCFB supplier?

As an established 2,4-Dichloro Fluoro Benzene supplier and distributor based in India and shipping worldwide, we work with a wide network of trusted manufacturers to combine consistent quality with dependable service. More about Chelora Agrochem.

High purity, every batch

99.5% min assay, sourced only from quality-approved manufacturers we have worked with and audited.

Full documentation

COA, MSDS and TDS travel with every order, so your QA and EHS teams are never chasing paperwork.

Reliable bulk supply, flexible MOQ

Single packs for process trials through to repeat container loads on schedule.

Worldwide supply

Export-grade packing, dangerous-goods documentation and on-time dispatch to plants across Asia, the Middle East, Europe, Africa and the Americas.

Technical & safe-handling support

Guidance on storage, PPE and process fit from a team that knows halogenated aromatic intermediates.

One point of contact

Source 2,4-DCFB alongside your other intermediates — one enquiry, one team, one invoice.

Ordering

How to order 2,4-Dichloro Fluoro Benzene from Chelora

Ordering is simple and fast — most enquiries are answered with pricing and availability within 24 hours.

  1. 1

    Send your enquiry

    Tell us the grade, quantity and application you are buying for.

  2. 2

    Receive a quotation

    We send pricing along with the COA and MSDS for your review.

  3. 3

    Request a sample

    Test suitability for your process before you commit to a bulk order.

  4. 4

    Confirm the order

    Lock in quantity, packaging and delivery preference.

  5. 5

    Dispatch & tracking

    We dispatch with full documentation and keep you updated until delivery.

Documentation

2,4-Dichloro Fluoro Benzene MSDS & COA

A summary of key safety information and a representative Certificate of Analysis. The complete 16-section Safety Data Sheet and the actual batch COA are supplied with each shipment — and both are sent with your quotation when you ask for a quote.

Safety data summary (MSDS)

SectionDetails
Hazard classificationSkin, eye and respiratory irritation; combustible liquid; aquatic chronic toxicity — exact categories on the SDS
Signal wordWarning
First aid — inhalationMove to fresh air; seek medical help if symptoms persist
First aid — skinRemove contaminated clothing; wash thoroughly with soap & water
First aid — eyesRinse with water for several minutes; get medical advice
HandlingUse PPE; avoid vapour and skin contact; ventilate; keep from ignition sources
StorageCool, dry, sealed; away from heat, ignition sources & oxidisers
EnvironmentToxic to aquatic life; prevent release to drains / waterways
TransportAs stated on the SDS

Certificate of Analysis (representative)

Test parameterSpecificationMethod
Assay (purity)99.5% minGC
AppearanceClear colourless liquidVisual
2,6-Isomer0.2% maxGC
Moisture0.05% maxKarl Fischer
ColourAPHA 20 maxAPHA
Density at 25 °C1.405 – 1.415 g/mLDensity meter

The actual batch COA is supplied with each shipment.

FAQ

Frequently asked questions

Common questions from buyers specifying 2,4-DCFB for fluoroquinolone, agrochemical and fine-chemical production.

What is 2,4-Dichloro Fluoro Benzene used for?

2,4-DCFB is used mainly to make 2,4-dichloro-5-fluoroacetophenone and 2,4-dichloro-5-fluorobenzoyl chloride, the key intermediates for the antibiotic ciprofloxacin. It is also used as a building block for agrochemical and fine-chemical intermediates.

What is the CAS number of 2,4-DCFB?

The CAS number is 1435-48-9 and the molecular formula is C6H3Cl2F. It is also known as 2,4-dichloro-1-fluorobenzene or 1,3-dichloro-4-fluorobenzene.

How is 2,4-DCFB used to make ciprofloxacin?

It is acetylated by Friedel–Crafts reaction to 2,4-dichloro-5-fluoroacetophenone, which is converted to 2,4-dichloro-5-fluorobenzoyl chloride. That acid chloride is built into the quinolone ring system of ciprofloxacin.

Is 2,4-Dichloro Fluoro Benzene hazardous?

It irritates skin, eyes and the respiratory tract, is a combustible liquid and is toxic to aquatic life. Handle it with proper PPE and ventilation, away from ignition sources; we supply a full MSDS with every order.

What is the difference between 2,4-DCFB and 2,6-DCFB?

Both have two chlorines and one fluorine. In 2,4-DCFB the chlorines are at the 2 and 4 positions relative to the fluorine; in 2,6-DCFB the fluorine sits between the two chlorines. 2,4-DCFB is the isomer used for ciprofloxacin intermediates.

How should 2,4-DCFB be stored?

In sealed drums or tanks in a cool, dry, well-ventilated store, away from heat, ignition sources and strong oxidisers, with bunding to contain spills.

Do you provide COA and MSDS for 2,4-DCFB?

Yes, we provide a batch-specific COA and MSDS with every order, plus technical support on request.

Do you supply and export 2,4-Dichloro Fluoro Benzene?

Yes, we supply 2,4-DCFB across India and export internationally with complete dangerous-goods documentation, sourced from reliable manufacturers.

Request a quote or sample

Need a reliable 2,4-DCFB supplier?

Looking for a dependable 2,4-Dichloro Fluoro Benzene (2,4-DCFB) supplier and distributor — in India or anywhere we export to? Tell us the grade and quantity you need — our team responds with competitive bulk pricing, samples and complete documentation (COA, MSDS, TDS) within 24 hours.

Request a quote Request a sample Request COA & MSDS Call +91 98191 11179 WhatsApp us

Or email source@cheloraagrochem.com