Herbicide intermediate
4-Fluoro-N-Isopropylaniline Supplier & Distributor in India & Worldwide
Chelora Agrochem is a trusted 4-Fluoro-N-Isopropylaniline (F.I. Aniline) supplier and distributor in India, connecting buyers with high-purity material sourced from leading, quality-approved manufacturers. Our N-isopropyl-4-fluoroaniline meets 98% min purity with controlled residual 4-fluoroaniline, full documentation and reliable bulk supply across India and to buyers worldwide.
As a specialised distributor of chemical products, we do not manufacture in-house — instead we source only from reliable, audited manufacturers, giving you dependable material, competitive pricing and a single point of contact for all your F.I. Aniline requirements, backed by COA, MSDS and TDS on every order.
- CAS number
- 70441-63-3
- Formula
- C9H12FN
- Molecular weight
- 153.20 g/mol
- Purity
- 98% min
Quick product specifications
4-Fluoro-N-Isopropylaniline at a glance
Identifiers, physical data and trade codes for F.I. Aniline. Batch-specific figures are confirmed on the Certificate of Analysis supplied with each consignment, in India and on export shipments alike.
- Chemical name
- 4-Fluoro-N-isopropylaniline
- CAS number
- 70441-63-3
- Molecular formula
- C9H12FN
- Molecular weight
- 153.20 g/mol
- IUPAC name
- 4-Fluoro-N-(propan-2-yl)aniline
- HS code
- 2921 42 90
- UN number
- UN 2810Toxic liquid, organic, n.o.s. — class 6.1, PG III
- Appearance
- Clear light-yellow to brown liquidNear-colourless when freshly distilled; darkens with air and light
- Boiling point
- ~214 °C
- Density
- ~1.045 g/mL
- Flash point
- ~83 °C
- Solubility
- Slightly soluble in waterMiscible with common organic solvents; log P ≈ 2.3
- Purity
- 98% min
- Moisture
- 0.2% max
- Synonyms
- F.I. AnilineN-Isopropyl-4-fluoroaniline · N-(4-Fluorophenyl)isopropylamine
- InChIKey
- RMXBOQCXULAXBO-UHFFFAOYSA-N
- Product form
- Liquid — drums, IBCs
- Documentation
- COA, MSDS & TDSSupplied with every order
Product overview
What is 4-Fluoro-N-Isopropylaniline?
4-Fluoro-N-isopropylaniline (N-isopropyl-4-fluoroaniline, F.I. Aniline) is a fluorinated secondary aromatic amine — 4-fluoroaniline carrying an isopropyl group on the nitrogen. Its principal industrial use is as the amine intermediate for flufenacet, an oxyacetamide herbicide for pre-emergence control of grass weeds, where the N-(4-fluorophenyl)-N-isopropyl amide is the heart of the molecule.
With the formula C9H12FN (CAS 70441-63-3), it is a light-yellow to brown liquid boiling at about 214 °C. It is made from Para Fluoro Aniline — or directly from 4-fluoronitrobenzene — by reductive alkylation with acetone, so both the fluorine and the nitrogen substituent are already in place when it reaches your plant.
Because the nitrogen already carries the isopropyl group, the amine acylates in one clean step to the tertiary anilide that flufenacet needs — which is why producers specify it closely by assay, residual 4-fluoroaniline and moisture.
How it is made
4-Fluoroaniline — or 4-fluoronitrobenzene, reduced in the same step — is condensed with acetone and hydrogenated over a metal catalyst, a reductive amination that puts the isopropyl group on the nitrogen. The crude amine is then purified by vacuum distillation.
What that means for your process
- Secondary amine ready for direct N-acylation
- Para fluorine retained intact through to the active
- Residual 4-fluoroaniline and over-alkylated by-products controlled to grade, checked by GC
- Low moisture for water-sensitive acylation with acid chlorides
Applications
What is 4-Fluoro-N-Isopropylaniline used for?
4-Fluoro-N-isopropylaniline is used as an intermediate in agrochemical and fine-chemical synthesis. Its main applications include:
Herbicides
The main use. It is the amine building block of the oxyacetamide herbicide flufenacet.
- Acylated to the N-(4-fluorophenyl)-N-isopropyl acetamide core
- Supplied to technical-grade manufacturers and synthesis units
- Process-development and route-scouting quantities
Pharma & fine chemicals
A fluorinated secondary amine for building N-aryl amides and heterocycles.
- Building block in custom and contract synthesis
- Fluorinated N-alkyl anilide scaffolds
Analytical
Used as a reference material in residue and quality work.
- Reference standard for flufenacet metabolite and residue analysis
- Reagent in analytical and research work
Process route
How is 4-Fluoro-N-Isopropylaniline used downstream?
The amine is acylated to the tertiary anilide, the side chain is converted to the hydroxy-acetamide, and that is coupled with the trifluoromethyl-thiadiazole partner to give flufenacet — with the fluorine and the isopropyl group both carried through unchanged.
4-Fluoro-N-Isopropylaniline
Charged as the secondary amine. Assay and moisture decide acylation yield.
C9H12FNN-Acylation
Reacted with a chloroacetyl or acetoxyacetyl chloride to form the N-(4-fluorophenyl)-N-isopropyl acetamide.
Acetanilide intermediateHydroxy-acetamide
The side chain is converted to the 2-hydroxyacetamide, ready for ether formation.
Hydroxy intermediateFlufenacet
Coupled with 2-methylsulphonyl-5-trifluoromethyl-1,3,4-thiadiazole and purified to technical grade.
Herbicide activeIn depth
4-Fluoro-N-Isopropylaniline applications by industry
Below is a detailed breakdown of where F.I. Aniline is used and the role it plays in each downstream product.
| Industry | Typical downstream products | Role of F.I. Aniline |
|---|---|---|
| Agrochemicals | Flufenacet (oxyacetamide herbicide) | Key amine intermediate |
| Agrochemicals | N-(4-Fluorophenyl)-N-isopropyl acetamides | Direct precursor |
| Pharmaceuticals | Fluorinated N-aryl amides and heterocycles | Building block |
| Analytical | Flufenacet metabolite reference standards | Reference material |
| Fine chemicals | Custom molecules | Precursor |
Safety
Is 4-Fluoro-N-Isopropylaniline hazardous?
Yes. 4-Fluoro-N-isopropylaniline is classified as toxic if swallowed or inhaled; it causes skin irritation, may cause an allergic skin reaction, is suspected of causing genetic defects, causes damage to organs through prolonged or repeated exposure and is toxic to aquatic life with long-lasting effects. With correct PPE, ventilation and containment it is safely handled in industry.
It should be stored in sealed containers in a cool, dark, well-ventilated place away from acids, acid chlorides, anhydrides and strong oxidisers. It is combustible (flash point about 83 °C) and darkens with air and light, so nitrogen blanketing is recommended for long storage. Prevent release to drains and waterways. A full MSDS is supplied with every order.
Signal word: Danger
Toxic if swallowed or inhaled · organ damage on repeated exposure · toxic to aquatic life
Safe-handling essentials
- Chemical-resistant gloves, goggles and face shield when handling the liquid
- Work with local exhaust ventilation; avoid breathing vapour or mist
- Keep drums sealed, cool and out of direct light; blanket with nitrogen
- Keep away from heat and ignition sources — the liquid is combustible
- Store away from acids, acid chlorides, anhydrides and oxidisers
- Never allow release to drains, soil or waterways
- Transport as UN 2810 — a regulated dangerous good
Grades
4-Fluoro-N-Isopropylaniline grades & technical specifications
We supply 4-fluoro-N-isopropylaniline in technical and high-purity grades to match herbicide, pharmaceutical and fine-chemical requirements.
| Parameter | Specification |
|---|---|
| Assay (purity) | 98% min — higher-purity grades on request |
| Appearance | Clear liquid, free from suspended matter |
| Colour | Light yellow to brown, as per grade |
| 4-Fluoroaniline (residual) | As per grade |
| Density | About 1.045 g/mL |
| Moisture | 0.2% max |
| Product form | Liquid — drums, IBCs |
Note: Values are representative. Batch-specific figures are provided on the Certificate of Analysis (COA) supplied with each consignment.
Supply
Packaging, MOQ & supply
From trial quantities for process validation to repeat container loads on contract — packed, documented and dispatched to your plant in India or overseas.
Packaging
200 kg MS or HDPE drums and 1000 L IBCs, nitrogen-blanketed, as per grade and quantity.
Minimum order quantity
Flexible — single drums for trials and route scouting through to full-container loads.
Shelf life
Long shelf life in sealed, unopened drums stored cool and dark under nitrogen.
Dispatch
Pan-India dispatch and worldwide export with complete documentation and logistics support.
Why buy from us
Why choose Chelora as your F.I. Aniline supplier?
As an established 4-Fluoro-N-Isopropylaniline supplier and distributor based in India and shipping worldwide, we work with a wide network of trusted manufacturers to combine consistent quality with dependable service. More about Chelora Agrochem.
High purity, every batch
98% min assay, sourced only from quality-approved manufacturers we have worked with and audited.
Full documentation
COA, MSDS and TDS travel with every order, so your QA and EHS teams are never chasing paperwork.
Reliable bulk supply, flexible MOQ
Trial packs for process work through to repeat container loads on schedule.
Worldwide supply
Export-grade packing, documentation and on-time dispatch to plants across Asia, the Middle East, Europe, Africa and the Americas.
Technical & safe-handling support
Guidance on storage, nitrogen blanketing, PPE and process fit from a team that knows fluorinated anilines.
One point of contact
Source F.I. Aniline alongside your other intermediates — one enquiry, one team, one invoice.
Ordering
How to order 4-Fluoro-N-Isopropylaniline from Chelora
Ordering is simple and fast — most enquiries are answered with pricing and availability within 24 hours.
- 1
Send your enquiry
Tell us the grade, quantity and application you are buying for.
- 2
Receive a quotation
We send pricing along with the COA and MSDS for your review.
- 3
Request a sample
Test suitability for your process before you commit to a bulk order.
- 4
Confirm the order
Lock in quantity, packaging and delivery preference.
- 5
Dispatch & tracking
We dispatch with full documentation and keep you updated until delivery.
Documentation
4-Fluoro-N-Isopropylaniline MSDS & COA
A summary of key safety information and a representative Certificate of Analysis. The complete 16-section Safety Data Sheet and the actual batch COA are supplied with each shipment — and both are sent with your quotation when you ask for a quote.
Safety data summary (MSDS)
| Section | Details |
|---|---|
| Hazard classification | Toxic (oral / inhalation); skin irritant and sensitiser; suspected mutagen; organ damage on repeated exposure; toxic to aquatic life |
| Signal word | Danger |
| First aid — inhalation | Move to fresh air; seek medical help |
| First aid — skin | Remove contaminated clothing; wash with soap & plenty of water |
| First aid — eyes | Rinse with water for at least 15 minutes; get medical advice |
| First aid — ingestion | Rinse mouth; call a doctor immediately |
| Handling | Use PPE; avoid vapour and mist; ventilate; keep from ignition sources |
| Storage | Cool, dark, sealed, under nitrogen; away from acids and oxidisers |
| Decomposition | Emits nitrogen oxides, carbon oxides and hydrogen fluoride on burning |
| Environment | Prevent release to drains / waterways |
| Transport | UN 2810; class 6.1; PG III; regulated dangerous good |
Certificate of Analysis (representative)
| Test parameter | Specification | Method |
|---|---|---|
| Assay (purity) | 98% min | GC |
| Appearance | Clear liquid | Visual |
| Colour | As per grade | Visual / APHA |
| 4-Fluoroaniline | As per grade | GC |
| Moisture | 0.2% max | Karl Fischer |
The actual batch COA is supplied with each shipment.
FAQ
Frequently asked questions
Common questions from buyers specifying 4-Fluoro-N-Isopropylaniline for herbicide and fine-chemical production.
What is 4-Fluoro-N-Isopropylaniline used for?
Its main use is as the key amine intermediate for the herbicide flufenacet. It is also used as a fluorinated building block in pharmaceutical and custom synthesis, and as a reference material in flufenacet residue analysis.
What is the CAS number of 4-Fluoro-N-Isopropylaniline?
The CAS number is 70441-63-3 and the molecular formula is C9H12FN. It is also known as N-isopropyl-4-fluoroaniline, F.I. Aniline or N-(4-fluorophenyl)isopropylamine.
How is 4-Fluoro-N-Isopropylaniline manufactured?
By reductive alkylation: 4-fluoroaniline — or 4-fluoronitrobenzene reduced in the same step — is condensed with acetone and hydrogenated, which puts the isopropyl group on the nitrogen. The product is purified by vacuum distillation.
Is 4-Fluoro-N-Isopropylaniline hazardous?
Yes. It is toxic if swallowed or inhaled, a skin irritant and sensitiser, suspected of causing genetic defects, can damage organs through prolonged exposure and is toxic to aquatic life. It must be handled with proper PPE, ventilation and containment; we supply a full MSDS with every order.
How is it related to Para Fluoro Aniline?
It is PFA with an isopropyl group added to the nitrogen. We supply both, so you can source Para Fluoro Aniline and 4-fluoro-N-isopropylaniline from one team — whether you run the alkylation in-house or buy the finished amine.
How should 4-Fluoro-N-Isopropylaniline be stored?
In sealed drums in a cool, dark, well-ventilated store, away from acids, acid chlorides, oxidisers and ignition sources. The liquid darkens with air and light, so a nitrogen blanket is recommended for long holding.
Do you provide COA and MSDS for F.I. Aniline?
Yes, we provide a batch-specific COA and MSDS with every order, plus technical support on request.
Do you supply and export 4-Fluoro-N-Isopropylaniline?
Yes, we supply 4-fluoro-N-isopropylaniline across India and export internationally with complete documentation, sourced from reliable manufacturers.
Request a quote or sample
Need a reliable 4-Fluoro-N-Isopropylaniline supplier?
Looking for a dependable 4-Fluoro-N-Isopropylaniline (F.I. Aniline) supplier and distributor — in India or anywhere we export to? Tell us the grade and quantity you need — our team responds with competitive bulk pricing, samples and complete documentation (COA, MSDS, TDS) within 24 hours.
Or email source@cheloraagrochem.com